Atherosclerosis is the development of plaques, or fatty hardenings, on the inner wall of … Deep vein thrombosis can cause leg pain or swelling, but also can occur with no symptoms.Deep vein thrombosis can develop if you have certain medical conditions that affect how your blood clots. + + As mentioned in the introduction to this section of the book, thrombosis plays a commanding role as a complication of highly prevalent disorders such as obesity, diabetes, and cancer. Boasting an impressive range of designs, they will support your presentations with inspiring background photos or videos that support your themes, set the right mood, enhance your credibility and inspire your audiences. Females are sheltered from disease from AS until menopause. Pathophysiology of DVT Virchow’s triad was developed to help identify the factors that were present in those patients who were developing DVTs. Atherosclerosis (cont’d) •It is a disease of the arterial intima leading to the formation of fibrous (“atheromatous”) plaques- proliferation of smooth muscle cells and the accumulation of lipids. With prompt diagnosis and treatment, the majority of DVT’s are not life threatening. outline. •If we have these deposits of cholesterol, the lipoproteins are modified, and so forth and so forth. •Multiple factors impose more than an additive effect (hyperlipidemia, hypertension, and smoking); heart attack rate is seven times greater than when none were present. Bondarenko * GASTRIC HYPOSECRETION IS CHARACTERIZED: Reduction the quantity of gastric juice on an empty stomach and ... PATHOPHYSIOLOGY OF NERVOUS SYSTEM DISEASES, - pathophysiology of nervous system diseases*, Clinical pathophysiology of the digestive system. objectives. Examples of Atherosclerosis of Human Arteries Microscopically, the aortic atheromatous plaque is thicker than the remaining media at the right. •Lowering cholesterol, especially LDL-C (so called “bad cholesterol”), is clearly a good thing. They'll give your presentations a professional, memorable appearance - the kind of sophisticated look that today's audiences expect. • Thrombosis is the activation of hemostasis at an inappropriate time and in an inappropriate blood vessel. Summary. Some DVTs may cause no pain, whereas others can be quite painful. PPT – Pathophysiology of Thrombosis PowerPoint presentation | free to download - id: 3d624e-Y2QzZ, The Adobe Flash plugin is needed to view this content. •Thrombosis is the final structural event leading to myocardial infarction or sudden coronary death. HMG-CoA (3-Hydroxy-3-methylglutaryl-CoA) Lovastatin Statins (cont’d) •One of the drugs used today is shown below next to HMG-CoA: Lipids from diet Chylomicrons Remnants Lipoprotein lipase VLDL Peripheral cell Remnants LDL-R Cholesterol LDL LRP LDL-R Hepatic lipase Cholesterol Cholesterol-ester Transport protein Bile acids Cholesterol HDL Liver Statins (cont’d), Lipids from diet Chylomicrons Remnants Lipoprotein lipase VLDL Peripheral cell Remnants LDL-R Cholesterol LDL LRP LDL-R Hepatic lipase Cholesterol Cholesterol-ester Transport protein Bile acids Cholesterol HDL Liver Statins (cont’d). symptoms . It can result in long-term complications that include postthrombotic syndrome (PTS) adding to its morbidity. Thrombosis/thrombophilia patients captured at HTCs participating in ATHN - . The coronary at the left is narrowed by 60 to 70%. 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